Palmitoylethanolamide

Raw materials offering:

English name: Palmitoylethanolamide

Alias Name: N- (2-Hydroxyethyl) hexadecanamide

More Alias: Palmidrol

CAS NO:. 544-31-0

Category: Synthesis

Molecular formula: C18H37NO2

Molecular Weight: 299.5

Appearance: white crystalline solid

Specifications: >98%

Detection methods: gas chromatography (GC)

Function: anti-inflammatory, to relieve pain

Palmitoylethanolamide (PEA) is an endogenous fatty acid amide, belonging to the class of nuclear factor agonists. PEA has been demonstrated to bind to a receptor in the cell-nucleus (a nuclear receptor) and exerts a great variety of biological functions related to chronic pain and inflammation. The main target is thought to be the peroxisome proliferator-activated receptor alpha (PPAR-α). PEA also has affinity to cannabinoid-like G-coupled receptors GPR55 and GPR119.PEA cannot strictly be considered a classic endocannabinoid because it lacks affinity for the cannabinoid receptors CB1 and CB2. However, the presence of PEA (and other structurally related N-acylethanolamines) has been known to enhance anandamide activity by a so-called "entourage effect".